Modeler

Modeler is a batch program which quickly and automatically generates a refined homology model of a protein, given only the sequence alignment to a known 3-D protein structure, using satisfaction of spatial restraints and simulated annealing techniques. Developed by Professor Andrej Sali (now at Rockefeller University), Modeler has been shown to generate excellent models with as little as 30% homology to known structures. It is interfaced to QUANTA for set-up and analysis of the resluting homology models.

Brenda Pfeiffer

.Marketing Specialist